'Numbness of the feet' is a poor indicator for polyneuropathy in Type 2 diabetic patients (2024)

Franse, L. V., Valk, G. D., Dekker, J. H., Heine, R. J., & Van Eijk, J. T. M. (2000). 'Numbness of the feet' is a poor indicator for polyneuropathy in Type 2 diabetic patients. Diabetic Medicine, 17(2), 105-110. https://doi.org/10.1046/j.1464-5491.2000.00223.x

Franse, Lonneke V. ; Valk, G. D. ; Dekker, J. H. et al. / 'Numbness of the feet' is a poor indicator for polyneuropathy in Type 2 diabetic patients. In: Diabetic Medicine. 2000 ; Vol. 17, No. 2. pp. 105-110.

@article{55aacd9b91b94adca624e90f8cc66ea1,

title = "'Numbness of the feet' is a poor indicator for polyneuropathy in Type 2 diabetic patients",

abstract = "Aims: To identify neuropathic sensory symptoms associated with a clinical neurological examination (CNE) and to investigate whether these symptoms could be used as a diagnostic or screening tool for diabetic polyneuropathy in general practice. Methods: Five hundred and eighty-eight patients with Type 2 diabetes, recruited from 26 general practices in the Netherlands, underwent a CNE and completed a diabetes symptom checklist that included 10 items on neuropathic sensory symptoms. Linear regression analyses were performed to assess the association between neuropathic symptoms and CNE. Receiver operating characteristic (ROC) curves were created to assess the diagnostic properties of neuropathic symptoms. Results: In this population, with a mean age of 66.8 years, 32% were identified with diabetic polyneuropathy according to the CNE. Variables that showed the strongest association with CNE score were age (β = 0.41), symptoms of sensory alteration (β = 0.27), and the item 'numbness of the feet' (β = 0.35) in particular. ROC curves showed that prediction of diabetic polyneuropathy from these symptoms was unsatisfying. The sensitivity and specificity of daily symptoms of 'numbness of the feet' were 28% and 93%, respectively, in patients < 68 years, and 22% and 92%, respectively, in patients ≥ 68 years. Conclusions: Identification of neuropathic sensory symptoms is not useful as a diagnostic or even a screening tool in the assessment of diabetic neuropathy in daily practice. Therefore, the results reported in this paper mandate an annual foot examination by the general practitioner.",

keywords = "Diabetic neuropathies, Neurological examination, Primary healthcare, Type 2 diabetes mellitus",

author = "Franse, {Lonneke V.} and Valk, {G. D.} and Dekker, {J. H.} and Heine, {R. J.} and {Van Eijk}, {J. T.M.}",

year = "2000",

month = mar,

day = "30",

doi = "10.1046/j.1464-5491.2000.00223.x",

language = "English",

volume = "17",

pages = "105--110",

journal = "Diabetic Medicine",

issn = "0742-3071",

publisher = "Wiley-Blackwell",

number = "2",

}

Franse, LV, Valk, GD, Dekker, JH, Heine, RJ & Van Eijk, JTM 2000, ''Numbness of the feet' is a poor indicator for polyneuropathy in Type 2 diabetic patients', Diabetic Medicine, vol. 17, no. 2, pp. 105-110. https://doi.org/10.1046/j.1464-5491.2000.00223.x

'Numbness of the feet' is a poor indicator for polyneuropathy in Type 2 diabetic patients. / Franse, Lonneke V.; Valk, G. D.; Dekker, J. H. et al.
In: Diabetic Medicine, Vol. 17, No. 2, 30.03.2000, p. 105-110.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - 'Numbness of the feet' is a poor indicator for polyneuropathy in Type 2 diabetic patients

AU - Franse, Lonneke V.

AU - Valk, G. D.

AU - Dekker, J. H.

AU - Heine, R. J.

AU - Van Eijk, J. T.M.

PY - 2000/3/30

Y1 - 2000/3/30

N2 - Aims: To identify neuropathic sensory symptoms associated with a clinical neurological examination (CNE) and to investigate whether these symptoms could be used as a diagnostic or screening tool for diabetic polyneuropathy in general practice. Methods: Five hundred and eighty-eight patients with Type 2 diabetes, recruited from 26 general practices in the Netherlands, underwent a CNE and completed a diabetes symptom checklist that included 10 items on neuropathic sensory symptoms. Linear regression analyses were performed to assess the association between neuropathic symptoms and CNE. Receiver operating characteristic (ROC) curves were created to assess the diagnostic properties of neuropathic symptoms. Results: In this population, with a mean age of 66.8 years, 32% were identified with diabetic polyneuropathy according to the CNE. Variables that showed the strongest association with CNE score were age (β = 0.41), symptoms of sensory alteration (β = 0.27), and the item 'numbness of the feet' (β = 0.35) in particular. ROC curves showed that prediction of diabetic polyneuropathy from these symptoms was unsatisfying. The sensitivity and specificity of daily symptoms of 'numbness of the feet' were 28% and 93%, respectively, in patients < 68 years, and 22% and 92%, respectively, in patients ≥ 68 years. Conclusions: Identification of neuropathic sensory symptoms is not useful as a diagnostic or even a screening tool in the assessment of diabetic neuropathy in daily practice. Therefore, the results reported in this paper mandate an annual foot examination by the general practitioner.

AB - Aims: To identify neuropathic sensory symptoms associated with a clinical neurological examination (CNE) and to investigate whether these symptoms could be used as a diagnostic or screening tool for diabetic polyneuropathy in general practice. Methods: Five hundred and eighty-eight patients with Type 2 diabetes, recruited from 26 general practices in the Netherlands, underwent a CNE and completed a diabetes symptom checklist that included 10 items on neuropathic sensory symptoms. Linear regression analyses were performed to assess the association between neuropathic symptoms and CNE. Receiver operating characteristic (ROC) curves were created to assess the diagnostic properties of neuropathic symptoms. Results: In this population, with a mean age of 66.8 years, 32% were identified with diabetic polyneuropathy according to the CNE. Variables that showed the strongest association with CNE score were age (β = 0.41), symptoms of sensory alteration (β = 0.27), and the item 'numbness of the feet' (β = 0.35) in particular. ROC curves showed that prediction of diabetic polyneuropathy from these symptoms was unsatisfying. The sensitivity and specificity of daily symptoms of 'numbness of the feet' were 28% and 93%, respectively, in patients < 68 years, and 22% and 92%, respectively, in patients ≥ 68 years. Conclusions: Identification of neuropathic sensory symptoms is not useful as a diagnostic or even a screening tool in the assessment of diabetic neuropathy in daily practice. Therefore, the results reported in this paper mandate an annual foot examination by the general practitioner.

KW - Diabetic neuropathies

KW - Neurological examination

KW - Primary healthcare

KW - Type 2 diabetes mellitus

UR - http://www.scopus.com/inward/record.url?scp=0034064549&partnerID=8YFLogxK

U2 - 10.1046/j.1464-5491.2000.00223.x

DO - 10.1046/j.1464-5491.2000.00223.x

M3 - Article

C2 - 10746479

AN - SCOPUS:0034064549

SN - 0742-3071

VL - 17

SP - 105

EP - 110

JO - Diabetic Medicine

JF - Diabetic Medicine

IS - 2

ER -

Franse LV, Valk GD, Dekker JH, Heine RJ, Van Eijk JTM. 'Numbness of the feet' is a poor indicator for polyneuropathy in Type 2 diabetic patients. Diabetic Medicine. 2000 Mar 30;17(2):105-110. doi: 10.1046/j.1464-5491.2000.00223.x